Fresh off the Tony triumphs of Hairspray, John Waters will write and direct A Dirty Shame for Killer Films, reports Variety. Described by Waters as "one family's comic descent into sexual dementia," the film will star Johnny Knoxville, Selma Blair, and Paul Giamatti. The lead female role, a convenience store owner who becomes a sex addict, has yet to be cast. "I wish Meryl Streep would do it, but I don't think she would," Waters tells Variety. "It has to be somebody real, who looks like they could belong in a convenience store, and in Hollywood these days, women in their 40s who look real are hard to find." He adds, "It's a sex education film that asks the question 'Can tolerance go too far?' It's also based on a really true fact, and I've of course exaggerated it. But there are a tiny percentage of concussion sufferers who have a carnal lust they cannot control. Of course, in this film, they take over a whole neighborhood."
Out indie film mogul Christine Vachon of Killer Films, who will produce with Ted Hope of This Is That, says, "The amazing thing about Hairspray winning everything Sunday [at the Tony Awards] was that it showed how John Waters can reinvent himself in new and invigorating ways. A Dirty Shame represents yet another reinvention and, in some ways, a return to the dangerous cinema of his roots."