Human trial of HIV vaccine to begin
BY Advocate.com Editors
January 01 2003 12:00 AM ET
Human trials of a novel DNA vaccine for treating AIDS in people already infected with HIV are planned to start in 2003, British company PowderJect has announced. Chairman and chief executive Paul Drayson said the vaccine, being jointly developed with GlaxoSmithKline, showed "proof of concept" in early preclinical studies and animal tests.
Unlike traditional vaccines, which use a weakened form of a virus to stimulate an immune response, DNA vaccines use a small portion of genetic material from the virus to elicit an immune system reaction that attacks HIV in the body. The vaccine in development is injected at high speed into the skin as a dry powder, eliminating the need for hypodermic needles.
The company hopes to have the vaccine on the market by the end of the decade. PowderJect also is developing DNA vaccines to treat herpes and some forms of cancer.
- WATCH: Elton John Slams 'Inhumane, Isolating' Anti-LGBT Laws In Russia
- Op-ed: Why I Filmed My Coming Out Journey
- Hot Sheet: Hark the Herald Angel Swings
- Nebraska Republican Vying for Mantle as Most Antigay in Primary
- Holiday Guide: Shop Here, Not There
- Lady Gaga Congratulates Tom Daley, Urges Boycott of Sochi Olympics
- Politics WATCH: Elton John Slams Russia's Anti-LGBT Laws Onstage 1 hour 39 min ago
- Women American Horror Story: Coven -- Ritual Witch-ual 1 hour 49 min ago
- Travel Wanna Win a Wedding in West Hollywood? 2 hours 53 min ago
- Election Nebraska Republican Vying for Mantle as Most Antigay in Primary 6:53 PM
- Women WATCH: Santana Lopez as the Best Bad Santa Ever! 6:33 PM
- Religion WATCH: Robertson Prays for Gays 'Recruited' By Abuse 4:41 PM
- Women WATCH: Idina Menzel's Female Empowerment Anthem from Frozen 4:07 PM