Protein patterns may identify HIV-positive people at risk for dementia

BY Advocate.com Editors

June 26 2003 11:00 PM ET

A study published in the journal Neurology shows that HIV-positive people experiencing symptoms of HIV-associated dementia have protein patterns different than HIV-positive people not experiencing dementia, suggesting a link between the proteins and dementia risk, Reuters Health reports. Researchers at the University of Puerto Rico and the University of Nebraska, using a technique called "proteomics protein fingerprinting," were able to identify patterns of protein activity in immune system cells and single out patterns linked with dementia. The study's findings could lead the way to a blood test to screen for the proteins, allowing doctors to identify HIV-positive patients at risk for the progressive degeneration of the brain that can occur in late-stage AIDS.

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