Biotech company
Vertex Pharmaceuticals on Tuesday said a mid-stage
clinical trial has shown its hepatitis C treatment lowered
virus levels to undetectable levels. The Phase II
trial enrolled 12 hepatitis C patients and dosed them
with Vertex' VX-950 treatment for 28 days. At the end
of the dosing period, all 12 patients had undetectable
levels of the hepatitis C virus. The company said it
also completed three-month studies on the treatment in
animals. Vertex plans to submit the Phase II data and
the animal studies to the Food and Drug Administration
sometime during the first quarter.
Hepatitis C is a
common coinfection among HIV-positive people. Experts
estimate that 25% of HIV-positive people are coinfected with
hepatitis C, and that as many as half of all
injection-drug users infected with HIV are coinfected
with hepatitis C. While there are vaccines that can
prevent hepatitis A and B infections, there is no vaccine
for hepatitis C. (AP, with additional reporting by
Advocate.com)