Study: Rates of HIV-induced dementia sky-high in Africa  | Health News | Advocate.com

Advocate.com health Channel
||  Health News  ||
 
January 31, 2007
Study: Rates of HIV-induced dementia sky-high in Africa

The rate of HIV-associated dementia is so high in sub-Saharan Africa that it has become one of the most common types of dementia in the world, according to an international study led by Johns Hopkins Medical Institution. Alzheimer’s and strokes are the other most frequent causes.

HIV dementia encompasses memory, learning, behavioral, and motor disabilities that interfere with normal daily life. In extreme cases, it can lead to total disability.

In the study, published in the current issue of Neurology, researchers found 31% of a small but representative group of 178 HIV-positive patients in Uganda were found to have HIV dementia.

"Clearly, large-scale testing would have to be conducted before we know the global reach of HIV dementia, but this study sends a clear message that it exists in high proportions in sub-Saharan Africa and is an underrecognized condition that needs to be studied and treated," said Ned Sacktor, a Johns Hopkins neurologist and senior author of the multi-institutional study.

Fortunately, HIV dementia, unlike the Alzheimer’s- and stroke-induced varieties, is treatable with antiretroviral medication. Treatment can restore completely normal cognitive function to some of those affected.

Dementia disrupts jobs, adds to the cost of health care, and also interferes with a patient’s ability to adhere to a regular course of antiretroviral medication, thus increasing the risk of drug resistance. People with dementia also are less likely to practice safe sex.

An estimated 27 million adults and children are HIV-positive in the sub-Saharan Africa. "If the rate we saw in our study translates across sub-Saharan Africa, we’re looking at more than 8 million people in this region with HIV dementia," said Sacktor.

Reader Comments

These comments are reproduced as written by visitors to this Web site. They have not been edited for content, grammar, or spelling. The viewpoints appearing here are those of the writer, and do not necessarily reflect the opinion or views of advocate.com, The Advocate, or its affiliates.

Be the first to comment on this story.

Back to top

Submit a comment for this story:

*Type your comment here (Required, 1000 characters max.):

*Name (Required): 

*Hometown (Required): 

*E-mail address: (Required, but will not be displayed)

Is this comment for publication? 
Yes   No

Daytime phone number: (Required for print publication only and will not be displayed)

Please enter the words you see in the box, in order and separated by a space. Doing so helps prevent automated programs from abusing this service.

  

If you would like to submit a comment for posting, please fill out the form above. 

All comments submitted via this form are subject to posting or publication. (To send a private letter to an Advocate editor or writer, please use the e-mail button at the top of the page, or use snail mail.) If you would like your comment considered for publication in The Advocate magazine, please include your full name, your city of residence, and a phone number where you can be reached during business hours so that we can confirm your identity. Your e-mail address and telephone number are strictly confidential and will not be shared or used for any purpose other than to contact you about your comment.

Comments that do not concern specific articles in The Advocate or on Advocate.com will not be posted or published. See the Contact page for sending comments for reasons other than responding to Advocate editorial and news stories.

Please note that comments sent by fax or snail mail are unlikely to be posted, although they will be considered for publication along with all letters received via e-mail or via this Web page. Comments that chiefly concern Advocate.com content will be considered for posting only on the Web site. The Advocate reserves the right to edit submitted comments for grammar, spelling, obscenities, or libel; we will, however, do our best to preserve the original comment's style and intent. Comments considered for publication in The Advocate magazine may also be edited for length.

More Exclusives
  • From the Great White Way to the White House
    While there won’t be a woman in the White House anytime in the near future, 24 took the reins and elected to cast two-time Tony Award winner Cherry Jones as its first female president, Allison Taylor, who is likely to have everything including terrorists, WMDs, and the kitchen sink thrown at her. Jones sat down with The Advocateto talk marriage, the White House, and her "fluid" relationship with partner Sarah Paulson.
  • Handicapping the LGBT Priorities of President-elect Obama
    As the Obama-Biden transition ensues, insights are surfacing into the new administration's agenda for gay Americans. While many of the policy pronouncements read like a list of old favorites, some lesser-known initiatives will likely gain momentum early on.
  • A Fortune 500 Take on Prop. 8
    The old saying goes that every cloud has a silver lining. And on November 5, the day after California voters stripped same-sex couples of the right to marry, so many around the country were searching for one. Although thousands of individuals, organizations, and businesses donated to the Yes on 8 campaign, not one Fortune 500 company is among those names. But on the opposite side, the side of fairness and basic rights, you’ll find some of the nation’s most successful and powerful corporate players.
  • Chevy Volt: The Jolt GM Needs?
    Launching a new vehicle while the American auto industry is asking Congress for a $25 billion bailout might seem like illogical timing, but for General Motors and the people behind Chevy Volt, it’s essential. With their backs against the wall, GM is rolling out their much-anticipated first plug-in electric vehicle -- and focusing their marketing efforts on the gay community.
  • Dr. Phil Weighs in on Prop. 8
    Advocate.com gets an early peek at a very heated episode of Dr. Phil. Gavin Newsom, HRC's Joe Solmonese, and L.A. attorney Gloria Allred face off against Prop. 8 supporters to talk same-sex marriage. In what may well be a first, Dr. Phil told the audience he would be keeping his opinions to himself.
  • An Unpopular Opinion: Blacks, Gays, and Prop. 8
    The injection of race into the analysis of Proposition 8's passage is extremely disappointing. A battle for equal rights has now turned into an issue of whites versus blacks. But while some black gays gay think marriage shouldn't be a priority and that outreach to African-Americans should have been stronger, journalist Clay Cane says he has a vested interest in inequalities related to both race and sexual orientation ... and he doesn't need someone to hold his hand into believing marriage equality is important.
  • Politics and Progress With Patti LaBelle
    The last time girl-group Labelle dropped an album, the thought of a black president or same-sex marriage seemed as “far-out” as the band’s disco-spacewoman suits and fusion of disco, rock, and soul. But the button-pushing, soul-singing trio has reunited, and on the heels of Prop. 8 passing and Barack Obama being elected president, Patti LaBelle talks to The Advocate about the mix of emotions she's dealt with over the past few weeks.
  • Seth Meyers's Big Gay Saturday Night
    SNL funnyman Seth Meyers talks to Advocate.com about last week's episode of Saturday Night Live -- the gayest episode in the history of the show, by some accounts. With touches including Justin Timberlake as Beyoncé's backup dancer and Snagglepuss crashing Weekend Update, it caused some bloggers to take offense ... but Meyers says it's just the sort of stuff that stemmed from many discussions about Prop. 8.
  • All Hands, Black and White, On Deck
    The high number of African-Americans who voted to pass Proposition 8 may have surprised some people, but not the folks at the National Black Justice Coalition, a civil rights organization dedicated to empowering black LGBT Americans. NBJC's CEO offers some insights about the black-white divide and how to mend it going forward.
  • Setting the Agenda ... the Gay One
    COMMENTARY: Prior to the election of Barack Obama, the gay rights agenda risked becoming nothing more than a wish list. But after nearly 30 years during which no major piece of gay rights legislation has been passed by both houses of Congress and signed by the president, it is time to make a a real push for true equality. Our time at the back of the bus must end. Now.
  • Survival of the Fittest
    Fallout 3 for Xbox 360 takes players on a pulse-pounding ride through postapocalyptic Washington, D.C.
  • Oscar-Winning Director Rob Epstein Remembers Harvey Milk
    When Rob Epstein released his 1984 documentary The Times of Harvey Milk, it didn’t simply serve as a memorial to Milk -- it gave him new life. For more than two decades, filmmakers have tried to turn Milk's life into a major motion picture. Screenwriter Dustin Lance Black and Gus Van Sant finally made it work, and Epstein, who calls the film "beautiful," takes a look back at the man who inspired a movement and what's become of California's gay community without him.
  • Building Bridges in the Wake of Prop. 8
    In the wake of finger-pointing following California's passing of Prop. 8, television writer and producer Tajamika Paxton suggests the time has come to build a bridge between the LGBT and African-American communities -- to engage in discussion rather than looking for somewhere to place blame.
  • Without Her We're Nothing
    The legendary Sandra Bernhard sits down with The Advocate before the one-night-only revival of her seminal one-woman show Without You I'm Nothing in Los Angeles to discuss Tori Amos, why Prop. 8 is "the best thing that could happen to the gay community," and how she she could possibly love both Rachel Maddow and Rachel Zoe.
  • Carmen Finds Her Spotlight
    It’s not very often that a lowly music critic gets the privilege of witnessing a glowing performance by a major new talent at the beginning of his or her career, but that is certainly what happened to yours truly on the evening of November 15 at the Los Angeles Opera. Viktoria Vizin, an astounding new mezzo-soprano making her L.A. Opera debut as Carmen this season, took my breath away.
  • Connecticut Gets Married
    This weekend, all 50 states participated in protests against the passing of antigay legislation in California, Arizona, Arkansas, and Florida. Gays and lesbians in Connecticut protested too, but they also had reason to celebrate. Last week, same-sex marriages got under way throughout the state.
  • Gay Is the New Black?
    In the wake of California’s passage of Proposition 8, protests are popping up around the country -- and so are comparisons between gays’ and African-Americans’ fights for equality. Is gay the new black? Michael Joseph Gross examines two struggles for civil rights. Plus: Photos from Wednesday night's rally in New York City.
  • The Day in Pictures
    From coast to coast, from gay to straight, from Pink to Mormon moms--a national movement to protest the passing of Prop. 8 in California rises up.
  • Smart Money
    In a time of economic calamity, one voice rises above the panic. Suze Orman is here to help -- she's offered her will and trust kit free to Advocate readers. Click the story for more info.
  • David Hyde Pierce is Gay, Married ... and Marching Against Prop. 8
    As Dr. Niles Crane on the hit sitcom Frasier, David Hyde Pierce had a great deadpan. That also extended to his own life: For years he wouldn’t confirm or deny being gay. Since then he thawed enough to thank his longtime partner, Brian Hargrove, in his 2007 Tony Award acceptance speech. And on Saturday, Pierce was one baseball-capped protester among maybe 20,000 others marching for equality in Los Angeles.