The award-winning author and civil rights activist died Wednesday at her home in Winston-Salem, N.C.
The effervescent trans woman was one of the first to sue for the right to survivor benefits in the late 1990s when her husband died of alleged medical malpractice.
Knuckles, a member of the Chicago Gay and Lesbian Hall of Fame, played a key role in developing post-disco dance music and worked with many big-name artists.
Reed, rumored to have had relationships with men as well as women, was one of the first rock stars to feature gay and transgender people in his songs.
The state funeral of legendary gay rights activist José Julio Sarria was a combination events: The social event of the season, a glittering photo op, and a deeply emotional tribute to a stellar figure in the LGBT movement.