Researchers at
the University of Texas Southwestern Medical Center,
in a study published in the March 26 issue of the Journal
of Experimental Medicine, reveal that a type
of lab mouse is susceptible to intrarectal HIV
infection, a common course of infection in humans.
This finding makes the mice useful for unprecedented
clinical trials and studies for vaccines, preventative
measures, and microbicides.
Researchers found
that when the mice were infected intrarectally with
HIV, the infection progressed the same way it does in
humans.
"We finally have
a way of following HIV in a system that is as close to
the human condition as you can get," said J. Victor Garcia,
the study's senior author and a professor of internal
medicine at UT Southwestern Medical School. Garcia and
his colleagues plan to study intravaginal HIV
infection in the mice as well. (The Advocate)
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