Health officials
in New York and Connecticut say they've discovered
the source of a strain of HIV reported in February in
a gay New York City man that was resistant to nearly
all anti-HIV drugs and rapidly progressed to AIDS,
United Press International reports. The man's
infection was not caused by a new, highly virulent
"superstrain" of HIV as was initially
feared, they now say.
Gary Blick, a
physician in Norwark, Conn., reports that he has a patient
who has been identified as the source of the strain of virus
that infected the New York City man. Blick's
patient and the New York City man had unprotected anal
sex at a sex club in October 2004, at which point the
Connecticut man transmitted the virus. The Connecticut
man's HIV strain was already resistant to most
anti-HIV drugs at the time he infected the New York
man, Blick says.
New York City
health officials quickly went public with the New York
man's case, worried that his infection may have been
caused by a new drug-resistant, rapidly progressing
strain of the virus. But Blick says they may have
sounded the public alarm prematurely, particularly because
he says his patient is now on a successful salvage drug
regimen of Sustiva and Fuzeon and has well-controlled
HIV infection. The same two drugs also are now being
used to successfully treat the New York City man, he
says.
Health officials
believe that the New York City man has unique immune
system factors that allowed HIV to rapidly deplete his body
of CD4 cells. Blick also says the man's use of
crystal methamphetamine and frequent unprotected
intercourse with multiple partners may be more of a factor
in the man's rapid development of AIDS than
anything having to do with the strain of virus he
contracted.
The New York man
admits to having unprotected sex with at least 10 other
men between the time he was infected with the virus and when
he learned of his infection. Efforts are under way to
identify and test those men but are hampered by the
fact that most of the man's sexual partners have
been anonymous hook-ups, health officials say. Blick says
it's possible that additional cases of the
drug-resistant virus will be reported in the coming
months if those men were infected during those sexual
encounters.