Ryan Murphy -- the gay producer of FX's Pose, American Horror Story, American Crime Story, and more -- is among those in the "titans" category. His entry was written by Jessica Lange, whose acting career experienced a revival in part due to Murphy casting her in AHS.
"He is a born storyteller, and, like the best of them, he is constantly pushing the limits. I have often marveled at his uncanny ability at capturing the zeitgeist," Lange wrote.
"Ryan is an artist of unlimited creative power and talent. But, more importantly, he has a great heart and is a dear and fiercely loyal friend. My life is better for knowing him."
Lady Gaga, the bisexual singer and lead of A Star Is Born who recently won an Oscar for the film's song "Shallow," was featured in the "icons" category. Coincidentally, Gaga stepped in as the female lead in American Horror Story: Hotel after Lange's departure from the series -- a role that garnered her a Golden Globe.
In her article, Celine Dion praised Gaga's artistry and individuality in her work -- but also how she uses her voice for social change.
Gaga "empowers her fans to adopt the very same values in their lives -- to stand up for what they believe in, despite what others might think," Dion wrote.
"By doing so, she gives her followers the strength and confidence to believe in themselves. Whether it's her unstoppable support for the LGBTQ community, or her anti-bullying campaigning, Lady Gaga's voice is being heard where it really counts."
Indya Moore -- one of the transgender stars of another Murphy-produced series, Pose -- was included in the "pioneers" category. Pose producer Janet Mock penned her praise of the actress and her role of carrying the torch of the trans rights movement with her visibility.
"In Indya, I see elements of our foremothers: the beauty of Sir Lady Java and Tracey Africa Norman, the brazenness of Miss Major and Sylvia Rivera, and the indelible warmth and spirit of Marsha P. Johnson. She is the living embodiment of our wildest dreams finally coming true," Mock wrote.
Time also honored Marlon James, the gay writer of A Brief History of Seven Killings, which won the Man Booker Prize, in its "pioneers" category. Salman Rushdie called James "one of the most important voices of his literary generation, a role he has gleefully embraced on social media and elsewhere, speaking out on race, literature, gay rights and whatever else is on his mind."
Since "influential" does not necessarily mean a force for good, the Time 100 also included several anti-LGBTQ figures, among them Donald Trump, Jair Bolsonaro, and Mitch McConnell.