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A new strain of Shigella is disproportionately impacting queer men. Why?

A new strain of Shigella is disproportionately impacting queer men. Why?
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Dr. Carlton Thomas, a gastroenterologist and host of the Butt Honestly podcast, knew something was wrong after having oral sex in the dark room play space of a Fort Lauderdale gay bar last year. Just a few days after returning home from the trip, he had developed diarrhea, dehydration, extreme fatigue, and a 104-degree fever.

As a gay GI doctor, Doctor Carlton, as his social media followers regard him, knew his symptoms could only be one thing: Shigella, an increasingly common bacterial infection that can spread through feces, usually via water contamination, unwashed hands, and, yes, certain types of sexual contact, especially when the anus and mouth are involved. Thomas tells The Advocate that he started having bloody diarrhea and eventually needed IV fluid bags, before getting treated with the antibiotic azithromycin. His symptoms subsided over the next 24 hours, but it left Thomas with a desire to raise awareness about the bacterial infection, especially how to prevent its spread.


“I was very lucky,” he says. “It felt like I was going to die.”

Shigella is the latest emerging sexually transmitted infection to uptick in recent years. Though Shigella has been a known bacterial infection since the 1890s, usually affecting young children in daycare settings, a new drug-resistant strain has been increasingly reported, and the population disproportionately affected has shifted. According to a report published in April in Morbidity and Mortality Weekly Report, the flagship publication of the U.S. Centers for Disease Control and Prevention, drug-resistant cases of Shigella have increasingly been reported by adult men who have sex with men.

While information from the CDC should be taken with a grain of salt these days, given the Trump administration’s effort to dismantle it and the agency’s politicization under Health and Human Services Secretary Robert F. Kennedy, Jr., LGBTQ+ medical experts agree it is a real concern, disproportionately being reported by queer men. Dr. Demetre C. Daskalakis, Chief Medical Officer at Callen-Lorde Community Health Center and former CDC chief vaccine officer, tells The Advocate that Shigella’s disproportionate reports among queer men boil down to several factors.

“We see higher reporting among men who have sex with men largely because certain sexual networks include sexual activities, like rimming, that can facilitate fecal–oral exposure,” Daskalakis says. “Men who have sex with men are also more likely to be tested for bacteria and parasites that cause diarrhea and counted among cases.”

As is the case with many illnesses that have disproportionately impacted queer people, however, this data is only part of the story.

“What’s missing is underdiagnosis in other populations, lack of routine testing, and stigma that keeps people from seeking care,” he continues. “Disease surveillance data often reflects access and trust in healthcare as well as the likelihood of medical providers to order the tests that diagnose Shigella.”

Experts say that this uptick in Shigella does not mean you have to close yourself off from the world or from sex. Rather than panic about the rise of Shigella or stigmatize people who have had it, healthcare professionals like Daskalakis and Thomas say it's important to understand how the bacterial infection spreads, get tested, get treated, and minimize transmission.

“We are in a vibrant era of PrEP and U=U, and now we even have DoxyPEP to reduce chlamydia and syphilis risk,” Thomas says. “People feel more free to have more sex, which is phenomenal! That comes with certain risks, though.”

What is Shigella?

According to Thomas, Shigella is a genus of bacteria that is highly contagious and includes several species, like flexneri, sonnei, and dysenteriae, all of which can cause an infection called Shigellosis and result in diarrhea.

How does Shigella spread?

The infection spreads through microscopic particles of fecal matter, which is why it was once most common in school settings with young children or in regions where clean water is hard to come by. It also means that if you are having sex that involves your mouth and anus, these particles can spread from an infected person to their sexual partner, or their sexual partner’s partner.

“It’s very contagious, and it doesn’t take much exposure to get sick,” Daskalakis says.

According to Thomas, it’s a common misconception that you can only contract Shigella from rimming or being rimmed. He said that he has actually had several gay men come into his office with no history of rimming who have contracted numerous enteric infections, or illnesses caused by microorganisms like bacteria, viruses, and parasites.

“With the rise of group sex in bath houses, dark rooms, and sex parties, I feel that there is a lack of understanding that you can get it from giving head to someone who just plowed someone else without protection and without cleaning off effectively or from being penetrated by someone rectally in the same scenario,” Thomas says. “This happens way more than people think.”

Even after someone receives treatment for Shigella, they can remain contagious for a few weeks, even if they no longer have symptoms.

“I feel that this is probably where most infections are spreading because many people get treated and then have no symptoms and go right back to sex,” he says.

How is Shigella treated?

Because cases of shigellosis can range from mild to life-threatening, treatment protocol greatly depends on what your doctor decides is the best course of treatment for your specific case. Usually, rehydration through oral or IV fluids is necessary, and in severe cases, a course of antibiotics may also be prescribed. Doctors stress that it’s important to start by confirming your diagnosis through testing if you suspect you’ve contracted it.

“Most cases don’t require treatment with antibiotics unless it’s a severe case or the person with the infection has a weakened immune system,” Daskalakis says.

How do you prevent Shigella from spreading?

Prevention begins with an understanding of the basics of how bacteria spread.

“Prevention is really about layering protections,” Daskalakis says. “Handwashing with soap and water, especially after using the bathroom or before eating, matters a lot. Avoiding sex when someone has diarrhea, and washing hands, bodies, and sex toys before and after sex can significantly reduce risk.”

If you’re engaging in group sex or sex in dark rooms, Thomas recommends taking a few extra precautions.

“Don’t bottom (especially in an unprotected group situation) or let someone eat your ass if you recently or are currently having bowel issues or were very recently treated,” he says. “You may be [infectious] for a few weeks after! (At least 2 weeks). At sex parties, if you are a top and penetrate someone (especially bareback), make sure you wash off thoroughly before you put it in the next person’s mouth or ass.”

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