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A tighter 2006 budget for the National Institutes of Health could force the world's top funder of medical research to pull the plug on some AIDS research and other projects that don't prove their value, a top official said on Monday. The Bush administration's 2006 budget calls for a $163 million, or 0.5%, increase in the NIH's $28.8 billion budget, said Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases. That compares with a doubling of the overall budget between 1997 and 2003. "Our belt is being tightened for us," Fauci told a news conference at the American Association for the Advancement of Science, saying that may hit HIV vaccine research especially hard. The Bush administration has proposed its tightest budget as it seeks to curb budget deficits that have soared on its watch. Fauci said HIV vaccine trials would have to meet certain intermediate goals, or "milestones," to get continued funding and may be stopped partway through to concentrate on more promising research. "Through the years, HIV/AIDS [research funding] has usually done at least as well as and usually better than other diseases," Fauci said. "However, as we now approach '06, '07, '08, and '09, it has become clear that not only will there be a less than 2% increase in the NIH budget, but that the previous largess that was associated with all research, particularly HIV, is now not going to be a reality for the future." Fauci said the heads of NIH institutes such as his had been told to reexamine the entire research portfolio. That will mean working even more with private industry and groups such as the nonprofit International AIDS Vaccine Initiative to get "the most bang for the buck," Fauci said. That will also mean setting milestones for clinical trials, such as many of the ongoing HIV vaccines trials. Those that don't show early results could be shut down, he said. (Reuters)
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