Researchers in
Iceland have discovered a genetic marker that indicates a
60% higher risk of developing prostate cancer, and they
report that African-American men are more than twice
as likely to carry the gene variant than white men,
reports the Associated Press. The researchers say the
higher rate of the variant in black men may help explain why
African-American men are more likely to develop prostate
cancer than white men.
The study of
nearly 2,500 men, published in the online version of the
journal Nature Genetics, showed that the DNA
variant was found in about 19% of white males who had been
diagnosed with prostate cancer but was present in
about 40% of black patients. The genetic variant may
also be linked with a higher risk of developing
particularly aggressive forms of prostate cancer, but
researchers say more studies need to be conducted to
confirm this link.
Iceland genetics
firm deCode plans to develop a genetic test for the
variant so that doctors will be able to identify patients
who may be at a higher risk of developing the disease.
In general, men face a 1-in-6 chance of developing
prostate cancer at some point in their lives. It is
one of the most common cancers among U.S. men; about 230,000
new cases are diagnosed each year. (The
Advocate)