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FDA approves new hepatitis B drug

FDA approves new hepatitis B drug

The Food and Drug Administration has approved a new drug for the treatment of chronic hepatitis B, the drug's manufacturer said Wednesday. The drug, entecavir, is taken orally and is designed to work by preventing the virus that causes the illness from reproducing. The chronic form of hepatitis B can permanently damage the liver and lead to cirrhosis and liver cancer. Entecavir is made by Bristol-Myers Squibb and will be sold under the trade name Baraclude. The company said it could be available in early April. Current treatment options for chronic hepatitis include interferon, given by injection, and two drugs administered orally, lamivudine and adefovir dipivoxil. In clinical trials the main side effects reported for the new drug were headache, tiredness, dizziness, and nausea. The Hepatitis B Foundation estimates that 1.2 million Americans have hepatitis B and another 100,000 are infected annually. The hepatitis B virus can be transmitted through sexual activity, particularly through oral-anal contact. The Gay and Lesbian Medical Association urges all sexually active gay and bisexual men to be vaccinated against hepatitis A and B, but fewer than half of the nation's gay men have received the vaccines. (AP, with additional reporting by Advocate.com)

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