Richmond,
Calif.-based biotechnology company Sangamo
BioSciences reports having created genetically
modified immune system cells that are resistant to HIV
infection, The Oakland Tribune reports.
Speaking at the 45th Annual Interscience Conference on
Antimicrobial Agents and Chemotherapy in Washington, D.C.,
Sangamo officials say they've developed immune
cells containing a genetic mutation that prevents HIV
from latching onto CCR5 receptors on the surface of
the cells, a portal HIV must attach to in order to infect
them.
Lab tests showed
that the genetically engineered immune system cells were
able to resist infection, even when exposed to high
concentrations of HIV. The researchers hope to advance
their findings to animal and human studies, with the
goal of engineering an individual's immune system
cells and reinserting them into the body, where they
would replicate and build a defense against the virus.
(Advocate.com)